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Poppers is a slang term for various alkyl nitrites inhaled for recreational purposes, particularly isopropyl nitrite (2-propyl nitrite) and isobutyl nitrite (2-methylpropyl nitrite), and now more rarely, butyl nitrite and amyl nitrite (isoamyl nitrite, isopentyl nitrite). Amyl nitrite is used medically as an antidote to cyanide poisoning, but the term “poppers” refers specifically to recreational use. Amyl nitrite and several other alkyl nitrites, which are present in products such as air freshener and video head cleaner, are often inhaled with the goal of enhancing sexual pleasure. These products have also been part of the club culture from the 1970s disco scene to the 1980s and 1990s rave scene. Poppers have a long history of use due to the rush of warm sensations and dizziness experienced when the vapours are inhaled.

Although, according to at least one analysis, poppers have a lower risk of harm to society and the individual than do certain other recreational drugs,other cases have shown that serious adverse effects can occur. In a letter to the New England Journal of Medicine, an ophthalmologist described four cases in which recreational users of poppers experienced temporary changes in vision. There is some evidence to indicate that even occasional use of poppers may affect vision.Accidentally swallowing or aspirating the liquid, rather than inhaling the vapours, is certainly dangerous and can prove fatal.

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